Moral injury presents many challenges to veterans and to the clinicians working with them. Recognition early on is important; however, many veterans experience shame and guilt and are reluctant to share the issues surrounding their moral injury with others. This talk will look at practical clinical approaches to treating moral injury in veterans, differentiating this from PTSD and other mental health conditions. We will explore the different underlying types of traumas faced by veterans, including threats to life, grief and loss and moral- and ethical-related traumas in the military, and which traumas lead to PTSD, to Depression and which specific traumas underly Moral Injury using brief clinical presentations. We will discuss how these traumas present differently in Moral Injury and look at early warning signs for veterans and the roles of shame and guilt in their presentation. We will examine the multitude of therapies, including adaptive disclosure therapy, Impact of Killing therapy, various cognitive-behavioural approaches, exposure therapies, the roles of chaplains and spiritual approaches, group therapies, peer-support, logotherapy and couple therapy working with veterans with Moral Injury. We will contrast these treatments and the approaches used in treating PTSD and look in addition to treatments that can be used in both PTSD and moral injury as well as treatments currently used in PTSD that should only be used with great caution when there is an underlying moral injury present. We will offer a practical clinical perspective on optimal treatment of Moral Injury in vetereans with and without concomitant psychiatric comorbidities.